DPCstruct | MC42694

Metacluster Properties and Pfam Annotations

Number of structural domains1923
Mean domain length (aa)162 ± 36 aa
Standard deviation of domain lengths35.80
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score87.19
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)22.54
Pfam Score98.73
Assigned Pfam label(s) PF13946- CL0592- CL0159- CL0128- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C8PHL0 984-1192 None
A0A5C8PBJ2 741-1018 None
A0A257EB41 527-698 None
A0A514C4B9 296-478 None
A0A317H3W3 842-1024 None
H8GI81 251-408 None
A0A839LW34 599-779 None
A0A839LSW8 244-417 None
A0A839LP34 250-395 None
A0A1B2I1R7 460-592 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.