DPCstruct | MC42694

Metacluster Properties and Pfam Annotations

Number of structural domains1923
Mean domain length (aa)162 ± 36 aa
Standard deviation of domain lengths35.80
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score87.19
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)22.54
Pfam Score98.73
Assigned Pfam label(s) PF13946- CL0592- CL0159- CL0128- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S0P9S6 672-816 None
A0A8A8VBZ7 306-517 None
A0A517NLX5 768-942 None
A0A318B7U6 9-135 None
A0A2T2W9R8 21-159 None
A0A1X7AQM1 913-1063 None
A0A3T0K6T4 53-269 None
A0A1I6M9W6 357-536 None
A0A1I6JM06 558-723 None
A0A7Y6V699 238-399 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.