DPCstruct | MC42694

Metacluster Properties and Pfam Annotations

Number of structural domains1923
Mean domain length (aa)162 ± 36 aa
Standard deviation of domain lengths35.80
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score87.19
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)22.54
Pfam Score98.73
Assigned Pfam label(s) PF13946- CL0592- CL0159- CL0128- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1C2EFX4 610-818 None
A0A858ZR07 539-773 None
A0A847KT90 272-408 None
B4WQE8 420-573 None
S3I6A8 17-200 None
A0A850KM73 378-552 None
A0A848W7N7 426-634 None
A0A2W6ETX4 6-112 None
A0A8B2NU44 439-648 None
A0A8B2NYT1 34-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.