DPCstruct | MC42694

Metacluster Properties and Pfam Annotations

Number of structural domains1923
Mean domain length (aa)162 ± 36 aa
Standard deviation of domain lengths35.80
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score87.19
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)22.54
Pfam Score98.73
Assigned Pfam label(s) PF13946- CL0592- CL0159- CL0128- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q3YRU4 497-699 None
A0A4Q3YPY0 185-306 None
A0A2W6D2L9 55-241 None
A0A347UKW2 236-445 None
A0A6H2CX62 320-537 None
A0A2H0QZR4 2-125 None
A0A2H0QZE2 265-425 None
Q166P1 9-195 None
A0A846G457 4-213 None
A0A3M1QAR8 270-447 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.