DPCstruct | MC42694

Metacluster Properties and Pfam Annotations

Number of structural domains1923
Mean domain length (aa)162 ± 36 aa
Standard deviation of domain lengths35.80
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score87.19
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)22.54
Pfam Score98.73
Assigned Pfam label(s) PF13946- CL0592- CL0159- CL0128- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7U0VD46 3-142 HANGGNDTVYSGSKNDTVYAGTGDDTLYGENGDDTLYGEEGKDTLYGGNGDDKLYGNEGDDTLYGDGGNDILVGGQGNDNLNGGAGD…
A0A433W4E1 2-86 SVIFGTDLDDSLTGGDGNDRIYGKAGNDNLNGNKGNDLLYGGVGDDRLLGGDGKDTLYGNENNDFLNGDAGDDTLYGGSGNDTLY
A0A7X4GUV4 13-134 None
W0BH99 213-326 None
B8ICV7 198-339 None
A0A316KVS2 343-529 None
A0A378N9P7 145-303 None
A0A378N7A0 457-692 None
A0A270AXS9 229-393 None
A0A1I3N8J5 284-396 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.