DPCstruct | MC42687

Metacluster Properties and Pfam Annotations

Number of structural domains708
Mean domain length (aa)215 ± 43 aa
Standard deviation of domain lengths43.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.38
Pfam Score82.17
Assigned Pfam label(s) PF03352- PF10576- CL0236- CL0198- PF10343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376U6W3 2-172 None
A0A4Q7JVQ1 44-285 None
A0A1Y4E133 23-227 None
A0A0A2VKK4 207-506 None
A9T041 3-171 None
A0A3S0Q017 1-236 None
Q2H5U8 48-392 None
L1LB25 432-656 None
A0A1W9QDH7 205-415 None
A0A421CAE6 5-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.