DPCstruct | MC42687

Metacluster Properties and Pfam Annotations

Number of structural domains708
Mean domain length (aa)215 ± 43 aa
Standard deviation of domain lengths43.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.38
Pfam Score82.17
Assigned Pfam label(s) PF03352- PF10576- CL0236- CL0198- PF10343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U0VUZ6 341-576 None
A0A5N6L2C7 53-246 None
A0A2Z6MQY8 193-445 None
A0A662VIK4 205-443 None
A0A1B9HJB8 313-535 None
A0A2V1AU24 450-694 None
A0A068V9U6 91-278 None
A0A4Q4TWR7 190-416 None
K0SBI7 384-543 None
A0A2D6P4Z8 10-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.