DPCstruct | MC42687

Metacluster Properties and Pfam Annotations

Number of structural domains708
Mean domain length (aa)215 ± 43 aa
Standard deviation of domain lengths43.44
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.38
Pfam Score82.17
Assigned Pfam label(s) PF03352- PF10576- CL0236- CL0198- PF10343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F5DC36 388-596 IFRRAETAVYKVLQEYPVESLQYNRDPFRGLVATMLSQNTNSKNQSTAYERLEEMVGITPENIDAALTVTIVEAIRPAGMYNQRSRA…
A0A7H0JYC5 3-182 TFAEDAGISLDDDPTSLFQLLVLCMLQAKPIRATVAVHAARGLFDAGLATPSALVEAPRSQLIRIFGDAGYARYDESTATRLHAMAS…
B0ENS0 2-140 None
A0A2V2EA54 321-531 None
A0A0W0CEC9 69-264 None
A0A2D5UGE0 97-325 None
A0A0B8PFQ8 9-172 None
A0A177WT25 2-169 None
A0A6V7PC99 75-420 None
A0A7C6EJC0 55-305 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.