DPCstruct | MC42678

Metacluster Properties and Pfam Annotations

Number of structural domains78
Mean domain length (aa)70 ± 10 aa
Standard deviation of domain lengths9.97
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score86.76
Mean fraction of residues predicted as intrinsically disordered0.51
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)47.68
Pfam Score100.00
Assigned Pfam label(s) CL0098

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0F3PW54 125-189 GVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDL
A0A510K4V5 17-90 VIKKESFETDSFYNGLLGFPQYTRPVEIDGYTVPEVLRSGNHAKIDEYRQFHSIEKTMKNRMDLFEKKLENIDE
B0MJQ4 71-137 None
A0A4Q4D2R3 160-224 None
A0A2M7WZL0 154-244 None
A0A4Q4Z9K8 162-225 None
A0A645JIV2 3-71 None
A0A7Y3LMT5 15-82 None
A0A7C6SBQ4 1-58 None
A0A2D7DV24 4-67 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.