DPCstruct | MC42658

Metacluster Properties and Pfam Annotations

Number of structural domains191
Mean domain length (aa)137 ± 29 aa
Standard deviation of domain lengths28.90
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score84.07
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)27.05
Pfam Score96.03
Assigned Pfam label(s) PF00238- CL0063- PF00189- CL0010- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
V5KV68 5-141 None
A0A2H5QMC0 461-577 None
A0A5A7QD41 295-445 None
A0A835ZIP8 267-448 None
A0A5D2ZHL8 11-172 None
A0A812UUW5 7-116 None
A0A553QS44 641-781 None
G3S8P5 14-154 None
A0A0A7A726 20-146 None
A0A1I8AI04 180-361 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.