DPCstruct | MC42654

Metacluster Properties and Pfam Annotations

Number of structural domains80
Mean domain length (aa)303 ± 73 aa
Standard deviation of domain lengths72.85
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score87.19
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)27.16
Pfam Score84.53
Assigned Pfam label(s) PF00940- CL0126- PF14700- PF13966

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5S6Q3H1 642-929 LVRLHYSSLPAAEVDKADVSEEEALPAMDCLNQLSGTPWIVNGPVLDVMLEVFRGKGNDALGIPPPPWTMPSFPKMPKQRMNTKEMA…
A0A6I9V3D1 3-175 DEDGFYYPHNLDFRGRAYPMHPYLNHLGSDLCRGILEFAEGRPLGKSGLRWLKIHLANVYGGGVDKLSYEGRVSFTENHLGDIFDSA…
A0A7J6U3V7 518-818 None
A0A0J7Y941 5-210 None
A0A661FPC7 156-394 None
A0A2G3CTQ6 7-208 None
M1V872 636-1017 None
A0A445JKJ1 25-377 None
A0A6J1EXZ5 2-304 None
A0A7C9F204 3-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.