DPCstruct | MC42634

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)161 ± 16 aa
Standard deviation of domain lengths15.99
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score81.57
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)30.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2BD72 1-131 MSQKPLRYLLNTKLKIPLTNVEVVKKLMKHPHWKTAGFHDIGKMLDYLMENFTVDEICANIHIVLYSRSVIEELLADLRKKYSQSTE…
A0A1Y1NKU2 7-144 SLSVLCYKPEQFIAFLQQGLNMHRHEEVTKFIQQLLGSHSRRIGVNLKKHVHHRCVNLSRIEDNYEYLRELNFSREAIINAIPVLLY…
A0A6P3UCM3 225-394 None
A0A6G0TQC6 71-248 None
A0A1Y1NFP2 65-206 None
A0A653DI43 137-299 None
A0A811WBF1 263-437 None
A0A2S2QG36 150-327 None
A0A0L7LD78 352-508 None
A0A7M7SRW4 184-346 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.