DPCstruct | MC42621

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)144 ± 16 aa
Standard deviation of domain lengths16.31
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score92.01
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)49.62
Pfam Score100.00
Assigned Pfam label(s) CL0603

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K9B5U0 3-148 LRNDALQMHKENQGKLEVTSKVKVTNKEELSLAYSPGVAEPCKDIHEDKRKVYDYTMKGITVAVVTDGTAVLGLGNIGAEASIPVME…
A0A171K2U4 1-151 MDANFRKAALEYHEHGRPGKISVTPTKQLSNQRDLSLAYSPGVAAACEEIVDDPVNVFRYTGRGNLVGVITNGTAVLGLGNIGALAS…
A0A1G4UDJ0 2-158 None
A0A0B8NJ84 2-108 None
A0A0K2RL19 1-135 None
A0A0T5Z150 1-157 None
A0A256WCL2 7-152 None
A0A2V2G218 188-339 None
A0A661NPT9 3-151 None
A0A1Q7GIV1 464-604 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.