DPCstruct | MC42620

Metacluster Properties and Pfam Annotations

Number of structural domains287
Mean domain length (aa)202 ± 39 aa
Standard deviation of domain lengths39.04
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.03
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.72
Pfam Score79.80
Assigned Pfam label(s) CL0362- PF05107

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J2S165 3-203 VWEVEIELLSDLHTAGERKGSVIDVLRRDGKVYLPGSHIKGVVRTEAERIWFGKNGKRICWVTGDPYGTEKEPAGIKPCEDRSGCPV…
A0A661D0E2 1-197 MSIKTIGIKYSEVNPLLLNNPQMVDPLNRYKKEASKITKKRNKTDDDHAELRTLEVEAKLYWDSDLGVYVPSSWVSSSIAQVAFKLE…
A0A1H9HCF6 122-376 None
A0A3M2DAJ1 2-203 None
I6Z4I9 2-168 None
A0A3M2C5M5 58-283 None
A0A6N7S527 25-267 None
A0A655FUD7 4-169 None
A0A4D8PRG9 1-343 None
A0A2H6A1Q8 1-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.