DPCstruct | MC42605

Metacluster Properties and Pfam Annotations

Number of structural domains167
Mean domain length (aa)180 ± 35 aa
Standard deviation of domain lengths34.92
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score74.62
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.58
Pfam Score98.60
Assigned Pfam label(s) CL0316- PF20146

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9L0J6 22-213 DILKNDPKVRFISRIVSSVNVSAECRESVRNTLQSFEGLEDWAFQMLNSWGDFPPKGVMEGTITDFGDYDQCLSIEPNLSIGRSQYC…
A0A060ZA78 2-138 NVSEKCTQDTRTFLSELNKDLPSEYAALMYDAFGKMGSDVLGGNVNRPGSLQECLSVQGPSFTGQYCQVFLKQDPIQYFVGICVPDS…
A0A7R9L4M2 13-152 None
A0A7R9KUH7 140-357 None
A0A0N1PH40 250-398 None
A0A7R9KE01 165-372 None
C3ZP78 22-177 None
A0A7R9KH26 91-334 None
A0A034VSD2 36-231 None
A0A4C1U2Y7 242-458 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.