DPCstruct | MC42599

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)299 ± 67 aa
Standard deviation of domain lengths66.96
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score83.20
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)22.38
Pfam Score0.00
Assigned Pfam label(s) CL0220- CL0271

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9KFS3 2-315 TCLLPTIERMDLLVKVFHRIERFPTVSINPLENQKMRLLFECYGQLIHKVIAGWDDSEVKYVFKTMQTIAHMEQRIQTIAKSPLGAR…
A0A6P3HD88 2-210 QTVVCSKPGSARKLELRIRLFCRNVLLDHWTHRSDSAFWLTCILKPWPMVNQARLLYIIFGPISPQDGQVVWQKMIEGPTDESCLKG…
A0A2B4SPK2 37-356 None
C3ZKF1 185-520 None
Q20775 173-499 None
A0A2A6B439 101-496 None
A0A821GY26 1-208 None
A0A3P8T0L9 105-408 None
L9JWW3 9-316 None
A0A0N4WG87 15-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.