DPCstruct | MC4258

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)374 ± 36 aa
Standard deviation of domain lengths35.66
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score82.83
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)25.07
Pfam Score85.32
Assigned Pfam label(s) PF17103- PF17102- PF11380

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y2DTK0 2-374 FLGMEHAPSDFFSPLFGPMMGFKSDSYNVKTLGGSGRWPTFGEKPFVYYTSYLLNHRFGLRSRHVQAHVAHSVSRAVMQEAMASFPQ…
A0A2R6S490 6-350 PTGNRFGSRYRPYVIHEAKSASLPLLQEISQMWSSQIANTALHPFRETKAGDGDISMMFMMVHFVVERWREALLWSWTVAKHGGLDD…
A0A4V4ML68 303-638 None
A0A0L0VY41 210-621 None
A0A146HFG3 827-1203 None
A0A066WIH4 737-1115 None
A0A165CR40 4-319 None
A0A165B3S8 159-529 None
L8X4Q5 29-426 None
M5BPU8 122-452 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.