DPCstruct | MC42564

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)240 ± 27 aa
Standard deviation of domain lengths27.42
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score70.64
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)44.57
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H3FK39 1-280 MADDSEPMPLPAPSRSNKARSDFASEIYDACLKGDETAIQAIASKNATWPSMLGEAMRHTREGSVTAREWIGVIANQMAEAGIDWVP…
W9Z7W2 1-229 MLGEAMRHTREGSVTAREWIDAITNQMAEAGIDWVPGYHCRRLTSRRVIQLDNGQRHERPVIVLTGPPNSPKREAKAAKLRLIIMAA…
A0A094KRQ6 35-270 None
A0A094G7Y8 80-296 None
A0A084QY64 1-206 None
A0A4V1RXQ9 386-658 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.