DPCstruct | MC42534

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)192 ± 31 aa
Standard deviation of domain lengths30.86
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.05
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)27.03
Pfam Score100.00
Assigned Pfam label(s) PF20232

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M5L5K6 16-199 AFLRGAGLPAEAIGTLTPELMELLGKMMNNCIQGTIDLLALRSLVKQEVKADVTVVVLRNNNPMKFFPDSQTVLTQMLRKKMPGFME…
A0A3P5XVY8 3-165 RLGRALRSMITGLREVLMTRASIKQEFRIGQTVIASGGNNPLKFSVSPEQAVEAMVRPGGPGWLPPDAAADQALQDLKAHEVAMLTG…
A0A251WN29 14-162 None
A0A7G6AER5 45-234 None
A0A509EMP8 2-145 None
A0A150P440 5-165 None
A0A376ZMA5 69-249 None
A0A1B8T7W8 13-210 None
A0A7W2BY60 108-335 None
A0A3M4Q256 15-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.