DPCstruct | MC42533

Metacluster Properties and Pfam Annotations

Number of structural domains115
Mean domain length (aa)346 ± 81 aa
Standard deviation of domain lengths81.17
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.61
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)14.36
Pfam Score56.19
Assigned Pfam label(s) CL0223- PF08495- PF10442- CL0271

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5MHU9 392-775 KTKVGYSENVDAYTSGVETAKMANKIENPQVGLLFTSCVQDQKEIMKGVKSVLKDIDIVGCTSSAAICTQDGYLNKPTGYSGMMLLG…
A0A496YMI3 36-415 IRKHPPSAVLAFASVCYELDELLAGVNEVVGDAPVLGATTAGEIMDGPHEKSVVVAILASPFLAVRIGIGRDASKGWNRAVAEAVGC…
A0A099P4T2 60-354 None
A0A6J7UZ23 141-521 None
A0A504WXM9 640-970 None
A0A6G0XRV4 319-673 None
A0A1Y2H4Y5 54-398 None
A0A357NC67 15-239 None
A0A1V9Y5K3 413-821 None
A0A7S2MI60 21-277 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.