DPCstruct | MC4252

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)94 ± 8 aa
Standard deviation of domain lengths7.84
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score83.42
Mean fraction of residues predicted as intrinsically disordered0.63
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.78
Pfam Score100.00
Assigned Pfam label(s) PF16170

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A223Q997 3-80 VQAHLAGHFSPLTGDYRWRGRLSPSPEVTAAFRAGARTVVVRTPDGFEGTGVLDEPNLWGGHPVNGAGSPPFAVPHVD
A0A849ADR5 187-277 DAAWYGPAEIELPDGERITVQAQLTGAMQPTDGQYHWQGHIAAADGLKPGTKIVVHAGGTPAPGRVSELTPWGSLHITGAGQPPFPL…
A0A5Q6S4B6 87-182 None
A0A0Q8WMU3 2-78 None
A0A7U1EF07 69-177 None
A0A7C3U9E7 1-96 None
A0A6G6WUX3 42-126 None
G7H1Z7 128-220 None
A0A7K3GCA7 2-94 None
A0A7L7M6C8 2-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.