DPCstruct | MC42513

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)620 ± 116 aa
Standard deviation of domain lengths115.95
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.18
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)16.20
Pfam Score47.47
Assigned Pfam label(s) PF04114- CL0105- CL0046- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H2TSH1 16-577 None
A0A7R9IE41 103-553 None
A0A448YPM2 19-575 None
A0A251QJ65 18-534 None
A0A7R8ZJ20 560-1142 None
A0A0N4YP62 6-569 None
A0A5N4B2X5 561-1209 None
A0A388K7A5 2-498 None
A0A0V0YJH8 1-612 None
A0A4P5W3Z6 3-489 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.