DPCstruct | MC4250

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)194 ± 20 aa
Standard deviation of domain lengths19.61
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score65.40
Mean fraction of residues predicted as intrinsically disordered0.77
Mean length-normalized TM-Score0.29
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.79
Pfam Score93.75
Assigned Pfam label(s) CL0020- PF08492

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q95SX0 2-208 WRQAAEFHLRGGASETAASSLEELLKLNPNDTKVLAQLVIAYAQFQPKRALELSRKLPKLETLTTASEIDALEAANWVMSAKAAKKT…
A0A7S3WMQ9 18-204 QALLRAAAAFYARHGRWEAAAAAHRRLLAKSPRDAATLAALVVAESHFDSEQAHESLARLEMMCPPLDDEPDASIDAEALEQAALPK…
B0BND9 36-222 None
A0A8B6BIF3 5-226 None
A0A812NQU8 656-814 None
H0EWX2 265-443 None
A0A1B9FSJ1 121-309 None
A0A813APZ1 256-447 None
A0A430Q2F0 158-390 None
I1K3J0 458-662 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.