DPCstruct | MC425

Metacluster Properties and Pfam Annotations

Number of structural domains5
Mean domain length (aa)266 ± 24 aa
Standard deviation of domain lengths23.92
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score90.92
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)22.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8RTZ0 1-288 MHRPRTSVSSAATRTTSSGRVTMAISLSYVPYKPKKFLSISMGGVKENDFVMVMGYPGSTRRYRESYSVAYNQDIAIPFQIDVFNKQ…
A0A2V8EWW5 82-373 ISILRAYQGTDGNHDEYDASHVPVKPGHHLRVTTSGVKEGDFTLVAGNPGNTNRYRESYSAEYNLRKGIPTQIEDLELHLGLLRKYA…
A0A6P4FYB2 216-489 None
A0A2D5UH51 130-364 None
A0A848QF67 177-416 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.