DPCstruct | MC4249

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)220 ± 43 aa
Standard deviation of domain lengths43.37
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.58
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)17.46
Pfam Score65.08
Assigned Pfam label(s) PF00122- PF00690- PF12409

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T0MH22 3-138 None
A0A444TBP0 42-240 None
A0A7J5XE17 189-428 None
A0A183C2M7 146-344 None
A0A820F0H8 21-243 None
A0A7J7JTS3 3-216 None
A0A7S1TW38 125-265 None
A0A176WML2 62-282 None
G7YUA5 317-457 None
A0A3R7K899 3-253 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.