DPCstruct | MC42472

Metacluster Properties and Pfam Annotations

Number of structural domains1041
Mean domain length (aa)248 ± 67 aa
Standard deviation of domain lengths67.30
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score85.46
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)13.91
Pfam Score59.97
Assigned Pfam label(s) CL0023- PF01131- CL0063- CL0324- CL0339

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R6KAE0 136-360 None
A0A2R6KAG6 420-665 None
Q18ER3 1216-1455 None
A0A1G2RXV3 17-196 None
A0A0J9XBH9 261-606 None
F0ZQH5 2-191 None
A0A2W0C7D1 52-258 None
A0A7C5BTN8 751-976 None
A0A2S7QY87 356-590 None
A0A0Q8PZC0 97-437 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.