DPCstruct | MC42472

Metacluster Properties and Pfam Annotations

Number of structural domains1041
Mean domain length (aa)248 ± 67 aa
Standard deviation of domain lengths67.30
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score85.46
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)13.91
Pfam Score59.97
Assigned Pfam label(s) CL0023- PF01131- CL0063- CL0324- CL0339

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A662QH30 45-286 KVLTERGWIRVSDLRKGDRLFIQPSGCFGKYGSTELGRILGWLVGDGQIDDDGRVTLWFYGKDKELATIIAEDVKKILGRSVRINEA…
H5SRB9 14-208 QKLALTDLQREILVGLLLGDACLETQNRGRTYRLKIEHSVAQAQYVQHLYHIFRDWVLQEPQIKRQRIAGKTYQKLWFNTVSHGAFR…
A0A2D6PI25 53-285 None
A0A2D6NYV4 113-334 None
A0A2D6NYR2 106-315 None
E6N3C0 193-403 None
A0A2D6NXM6 110-411 None
A0A0F9UEH8 32-371 None
A0A1Q7DKI5 15-197 None
A0A2D6G7Q2 24-321 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.