DPCstruct | MC42462

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)149 ± 10 aa
Standard deviation of domain lengths10.16
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score86.54
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)22.38
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A557QFG8 1-142 MPRIVSPSAAESFLFAAQGLFDGAEALEAPSSRQPLACAFLSAQALECTLKAFLSHSGMDQRQLKSIGHNLEKLWTQAASAGLVVSE…
A0A154R1S6 2-134 LRYAEYYRIAAEQVIGDCNPLESRLLMLAYNLIAQSIELSLKAYLLSKGLKNSRLRGPLLGHNLSGLIAEAESLGLNNLVSLDDLDR…
A0A7X6FH26 228-374 None
A0A3A5JSM9 11-169 None
A0A7V2GYU8 17-168 None
A0A418KZV2 7-169 None
A0A546YVU4 141-284 None
A3TTL7 1-160 None
A0A7Y4LWG0 2-152 None
H0SJE3 1-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.