DPCstruct | MC4246

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)123 ± 17 aa
Standard deviation of domain lengths17.38
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score70.06
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)31.59
Pfam Score100.00
Assigned Pfam label(s) PF07253

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q6IL17 1-122 MLLLTNFNGTLRTAAENYDLIGSFIIQFDNETIMVNGQNYSSYSVSHLMAMPAVLSHITASNFQLSLEYVHDVSMKNLEKMSNMASE…
A0A7R8UD92 191-313 LFNDFKGKVEINGTEQDLRGTYLIKFKNITITVNNQSYRSLETTNIQLLPPLLHVGIEKDELVEILSMELIKEMHINNTRQIKLLEA…
A0A1A9WPF4 29-174 None
A0A811VJB2 195-316 None
A0A1B0BKR6 87-208 None
A0A1A9V8F0 109-196 None
A0A6P8JFI2 8-138 None
A0A811UTW4 48-195 None
B4NV57 37-152 None
A0A7R8YVW4 1-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.