DPCstruct | MC42436

Metacluster Properties and Pfam Annotations

Number of structural domains92
Mean domain length (aa)104 ± 15 aa
Standard deviation of domain lengths14.55
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score84.36
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)25.90
Pfam Score97.92
Assigned Pfam label(s) CL0179- PF14319

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A353RZ79 6-112 HISKVTFKQIFIDHWESFKQNCHLYDTVYYDSVINKMINCGDPEKMGYAKYRCIYCGSSYTISMTCKSCFCLSCSVPYADRWIDFIG…
A0A080M2Y8 1-70 MGAIQEIFRRHGPAYLAEFGKTLPGSHARVIEAIIDCRSAACGSVFYQCEDCGEPHVAARCCGNRHCPVC
A0A7X1P9G5 8-112 None
A0A3D6C8N0 10-79 None
A0A136LJB9 7-112 None
A0A1H4GHX2 4-104 None
A0A377HGR2 71-172 None
A0A084Y5N2 10-129 None
A0A533QIU0 3-103 None
A0A376E240 9-106 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.