DPCstruct | MC42435

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)138 ± 19 aa
Standard deviation of domain lengths18.52
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.61
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)14.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0LQD8 113-209 ASMDRAEAEAMLAKPLDIRGARIVFDGKACEGIRFSRTKEKLSAYLERVYKIGPKDLELTDQLIEVIRTDCGLPGFQEYMRLGDRRL…
A0A0Q7X6U9 4-121 AIFGTWKITQVADGQDSTSISDEEAAATVGLPLQIGPDTIRFGKANCAAPVFRTTRRRTYTYFVRQFNFDPQSLHLPDSVLEIEVKC…
A0A2A4G5N2 27-151 None
A0A2V8SQ60 148-258 None
A0A2E6KJX5 38-160 None
A0A3E1S3E2 25-152 None
A0A5R9PHM3 55-197 None
A0A5F1UJ11 12-164 None
A0A7U9R7M4 356-511 None
A0A399RSQ2 21-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.