DPCstruct | MC42432

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)244 ± 33 aa
Standard deviation of domain lengths32.75
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score68.53
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)27.01
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A673WCY8 62-301 SDESSHDSLEEIEDISDSGSDFEVQLKAMKRRKQTTALLGPRPPKRPRHKAASQASPNPSTTSTPPARSPQPPQPSLGRTRQLGSPR…
A0A1M8ABR5 20-279 SDTEEEEVDTPPLPTKRGRQTTTFDSDSSLSDLSEEEAPQPAPKRSRTRKTVEYAPDVSETSDSELFQAVLAAEGLDEAAENWVMAF…
A0A3F2RMX4 24-229 None
A0A817NDV1 27-256 None
D7G0R2 94-367 None
A0A6I9MVJ9 7-230 None
U9SVZ2 316-525 None
A0A2G9SCG1 54-288 None
A0A3Q3W8Y8 1-186 None
A0A5N4CXP3 3-273 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.