DPCstruct | MC42422

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)212 ± 30 aa
Standard deviation of domain lengths30.39
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score80.73
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.88
Pfam Score100.00
Assigned Pfam label(s) PF19877

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A538AAC1 3-228 RARAVVFGGWRMLLAGLALSFVGLLVLAAVKPGARPIAYNIPTSSGSDAVGGTVFTVLTVPNRAALALFPSMGSCLGVFANVQGADV…
A0A1D2QE19 6-170 LASFCTRGFTFGLLSYLVGYLLVAALFVVGPANVKGPLDVKLKWFGFAFYNAHFIPIAIGSQSYNYISQASDPAVPPIVYYAIPVVS…
T0CY68 18-195 None
A0A4V1FX92 27-223 None
A0A2M9KZI2 57-251 None
A0A087C117 63-305 None
A0A6J6ACV8 1-176 None
A0A401ZUW7 395-625 None
A0A150KZL3 18-255 None
A0A6G2BF06 226-444 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.