DPCstruct | MC42343

Metacluster Properties and Pfam Annotations

Number of structural domains100
Mean domain length (aa)146 ± 34 aa
Standard deviation of domain lengths33.83
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.05
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)23.42
Pfam Score95.80
Assigned Pfam label(s) PF17042- PF07005- CL0064

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A239QVV5 283-472 None
A0A0S8AAR7 258-435 None
A0A0P6W9H4 286-472 None
A0A4R7KSV6 18-154 None
L8TSE0 14-153 None
A0A453RAV4 10-140 None
A0A4R0X959 2-124 None
A0A365CZP3 250-425 None
A0A453RAS3 42-216 None
A0A1V5GMC7 1-103 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.