DPCstruct | MC42343

Metacluster Properties and Pfam Annotations

Number of structural domains100
Mean domain length (aa)146 ± 34 aa
Standard deviation of domain lengths33.83
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.05
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)23.42
Pfam Score95.80
Assigned Pfam label(s) PF17042- PF07005- CL0064

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A515EV09 284-420 AQPVAPSPWRVSAAPWVLVGSVNPVSHAQAATLALACPTVPLLLTRLVRSDPLTATQALVAQLAQAIQSGQCDGVVVTGGETAKALA…
A0A447L1Z4 2-102 YATAEPDTLQQIQRQYGVDAASHAVEALFAALVKQLQQAGFSRFIVAGGETSGVVTQALAIRGFHIGPCISPGVPWVRAIEQPVSLA…
A0A0S9D6Y8 2-79 None
A0A377M0R9 8-84 None
A0A345XTV3 291-452 None
A0A5N5K3P2 38-236 None
C9SN39 26-199 None
A0A2E2YTC9 37-181 None
A0A835UG38 428-610 None
A0A1Q6V0P2 298-467 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.