DPCstruct | MC42325

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)68 ± 5 aa
Standard deviation of domain lengths4.83
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score86.53
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)48.60
Pfam Score100.00
Assigned Pfam label(s) CL0459

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452Z112 258-323 AEQLGAVCCSEVDPSVTHVVAVHAGTEKARWAVKHKKFLLHPRWIEACNYRWHRQPEEDFPVPGLK
A0A251UAC3 494-560 AERLGATCSTEVDSSVTHVISTDIGTEKSRWAIQENKFLVEPRWLEAANFLWQRLPEESFPVKFPDV
A0A7S1T245 116-183 None
A0A061DZA3 170-237 None
A0A067GKL5 218-279 None
A0A6P5MHS5 192-256 None
A0A830CWN5 1-70 None
A0A2P6QK53 8-88 None
W1NPN8 531-595 None
A0A452Z119 132-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.