DPCstruct | MC42279

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)108 ± 18 aa
Standard deviation of domain lengths17.87
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score86.83
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)37.54
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287XKU2 87-193 VPPGLVDELVEEALVWCSQHGLVVGDKNHPRSGKAPGVGLLHAPFALLPMSFPKVYWEQALELAPLFNELVHRVSLDGDFLQQTLAR…
I1NC20 83-196 DQKLLQNIVYDALVWSTLNCLLVGDKSVQRSGRVPGVGLVHLPLSLLPGPFPESHWKQGCELAPIFNELVDRVSLDGKFLQESLSRT…
A0A2H2I6E8 17-123 None
A0A4U5M0F6 13-117 None
A0A287XKJ7 74-197 None
A0A821CDP5 11-112 None
A0A803Q021 7-120 None
A0A7R9B7C0 1-84 None
A0A1D6F7V7 2-118 None
A0A835SD65 139-249 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.