DPCstruct | MC42246

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)54 ± 5 aa
Standard deviation of domain lengths5.24
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score83.60
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)72.62
Pfam Score94.44
Assigned Pfam label(s) PF03386- CL0431

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445D3Q3 8-59 GAVIRGKKGLGGVTIKKTNQALIIGIYDELMTPGQCNMIVERLGDYLIDTGL
A0A6A4Q0I7 1-45 MGPGGVTVKKTNQALIIGIYDEPMTPGQCNMVVERLGDYLIDQGL
A0A5J9VHH5 700-758 None
A0A0E0JF32 73-131 None
A0A287VP43 15-68 None
A0A1R3H9E7 73-129 None
A0A540KK50 160-213 None
A0A803NU51 38-94 None
A0A5P1FR11 368-426 None
A0A5P1EP93 66-109 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.