DPCstruct | MC42230

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)214 ± 46 aa
Standard deviation of domain lengths46.30
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.14
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)31.32
Pfam Score65.97
Assigned Pfam label(s) CL0031- CL0340- CL0493

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A484Y8G2 2-220 GVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAY…
R5TGC8 156-289 LGVLLAYMFFCKDKKTKQSAPGAVIIHVLGGIHEIYFPYILMNPLVIIAPIVGNMAAVFWFNLTDCGLVGPASPGSIIAYLMMTPGP…
A0A0N0I528 2-176 None
U7VC40 377-628 None
A0A1Q2D0J5 23-233 None
A0A6N6X7A9 2-165 None
A0A1Q9YEH9 78-250 None
A0A1Q6U7E7 2-212 None
A0A7X2MDX8 28-252 None
A0A116R1B7 39-317 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.