DPCstruct | MC42223

Metacluster Properties and Pfam Annotations

Number of structural domains17503
Mean domain length (aa)261 ± 60 aa
Standard deviation of domain lengths60.04
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.89
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.77
Pfam Score97.56
Assigned Pfam label(s) PF06146- PF08492- CL0003- CL0219- CL0366

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3AQ80 337-573 None
H3AVC5 29-305 None
H3B463 432-715 None
H3B4P5 8-354 None
A0A370PEY6 483-675 None
A0A814U0I2 77-331 None
A0A370PXB8 3-311 None
L0D9Y1 65-353 None
L0DK82 79-377 None
L0DLR9 77-385 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.