DPCstruct | MC42223
Metacluster Properties and Pfam Annotations
| Number of structural domains | 17503 |
|---|---|
| Mean domain length (aa) | 261 ± 60 aa |
| Standard deviation of domain lengths | 60.04 |
| Length coefficient of variation | 0.23 |
| Mean AlphaFold2 pLDDT confidence score | 78.89 |
| Mean fraction of residues predicted as intrinsically disordered | 0.22 |
| Mean length-normalized TM-Score | 0.46 |
| Mean intra-cluster local Distance Difference Test score | 0.46 |
| Mean intra-cluster sequence similarity (%) | 16.77 |
| Pfam Score | 97.56 |
| Assigned Pfam label(s) | PF06146- PF08492- CL0003- CL0219- CL0366 |
Seed Sequences
Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.
| Protein ID | Range | Seed Sequence |
|---|---|---|
| H3DUV8 | 491-779 | None |
| H3DXY4 | 325-618 | None |
| H3E5V6 | 69-393 | None |
| H3EC19 | 372-713 | None |
| A0A319DAB8 | 39-329 | None |
| A0A319DMB1 | 67-394 | None |
| A0A319DP05 | 923-1097 | None |
| A0A2N1SVR8 | 243-546 | None |
| R5GQI7 | 2-200 | None |
| A0A7T4NIZ0 | 9-245 | None |
3D Structure Viewer
A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.
AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.