DPCstruct | MC42223

Metacluster Properties and Pfam Annotations

Number of structural domains17503
Mean domain length (aa)261 ± 60 aa
Standard deviation of domain lengths60.04
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.89
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.77
Pfam Score97.56
Assigned Pfam label(s) PF06146- PF08492- CL0003- CL0219- CL0366

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8LM21 4-219 None
A0A091CJE8 292-509 None
A0A091CMN6 363-553 None
A0A091CPQ7 515-779 None
A0A091D5Z4 14-292 None
A0A6A5BX86 357-646 None
A0A6H5KCK3 445-604 None
A0A6H5KMH0 203-625 None
A0A6H5KQ31 137-395 None
A0A6H5KS20 229-522 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.