DPCstruct | MC42223

Metacluster Properties and Pfam Annotations

Number of structural domains17503
Mean domain length (aa)261 ± 60 aa
Standard deviation of domain lengths60.04
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.89
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.77
Pfam Score97.56
Assigned Pfam label(s) PF06146- PF08492- CL0003- CL0219- CL0366

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A375HCL8 265-585 None
A0A4Q5XHY6 20-339 None
A0A4Q5XK31 159-449 None
A0A4Q5XKQ3 15-202 None
A0A4V2AJ49 11-267 None
A0A6V1P443 123-430 None
A0A6V1TUH8 411-694 None
A0A7S3UTA3 2-163 None
A0A7S3V033 36-267 None
A0A1F2R3D6 11-228 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.