DPCstruct | MC42223

Metacluster Properties and Pfam Annotations

Number of structural domains17503
Mean domain length (aa)261 ± 60 aa
Standard deviation of domain lengths60.04
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score78.89
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)16.77
Pfam Score97.56
Assigned Pfam label(s) PF06146- PF08492- CL0003- CL0219- CL0366

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I2DGQ5 14-261 None
A0A843WV84 107-305 None
A0A3Q0J9A2 37-190 None
A0A3Q0JAN5 83-352 None
A0A3Q0JDG9 119-407 None
A0A1H9PZF5 32-290 None
A0A0D3H5K1 274-614 None
A0A5P1EWN0 364-681 None
A0A5P1F2C7 27-210 None
A0A5P1FAH8 571-790 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.