DPCstruct | MC42222

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)174 ± 12 aa
Standard deviation of domain lengths11.55
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score77.31
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)29.32
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I8EZ96 1-194 MLSGSPGGPTGALTSLFGGTRAIDQLMSLSQRPEMAMALGALGLGKLGRQSIDVGPSRVPVPTAAFPNLYAQLADQVVTEAAELAGD…
A0A2V7YA66 1-181 MPQPYDQIGMLIQALRQHQIPPLPGLVPAVPPAVPQADGLGLLRMILGNPQFQQAMHFASVLGPAAPRTVQLPVPTGAVPGTRSVAI…
A0A849EQT3 197-366 None
A0A3N1JIT4 93-281 None
A0A2T1D180 1-177 None
A0A246JE69 189-354 None
A0A370WY82 83-243 None
A0A4P7LH56 209-372 None
A0A6G9YLP9 47-207 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.