DPCstruct | MC42220

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)472 ± 77 aa
Standard deviation of domain lengths77.18
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.23
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)19.27
Pfam Score75.00
Assigned Pfam label(s) CL0328- PF00504

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A090W630 1-409 MNTLASEFLRKLSRKPYFKYTENGKSIRYSANQAFLAMQSAPNIWQYVPLIKVDPKKGGELFSNLSINENGLVSFSELLEKEGKYLL…
A0A2V7XVV8 1-447 MMTQKRRIGTTTPLFCAVAVTLSALAATDARAATPVDALRTVAIQDGGRIKPLDTFSRETARRITGARAFGAESVRGLDPVEWVVAM…
A0A6B2M5B9 9-516 None
A0A2V8ER12 2-440 None
A0A520LF05 58-721 None
A0A2D5B8Z1 152-686 None
A0A800APL9 98-581 None
A0A2K1L3R7 16-445 None
A0A2A5AD89 22-428 None
A0A2V2S4K8 2-398 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.