DPCstruct | MC42169

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)159 ± 24 aa
Standard deviation of domain lengths23.63
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.33
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.78
Pfam Score98.53
Assigned Pfam label(s) PF05786- PF06127

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7L4R7 3-160 LFDLEKHFAFYGAYHSNPINVLIHMVFVWPIAFSLSVLLYFTPSIFNFLPQIHFSLLGNDFHLIFNLGFCLTLIYCLFYISFDIKAG…
A0A6M4H4B0 4-156 LAENLTQYAAYHRDRRNIATHFVGVPMIVFAIVLALATMSLPLDLGFPVTIAALVCVAGCAYYLWLDLTLGVAMVATMFVMLAMSSE…
A0A2S4L8A8 58-238 None
A0A1S8W208 8-175 None
A0A6P8HLE5 11-195 None
A0A1V8T449 1-174 None
A0A0A9DHW9 6-105 None
A0A7Z2RLZ6 4-133 None
W2PZ23 7-145 None
A0A0B7NTX5 294-461 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.