DPCstruct | MC4212

Metacluster Properties and Pfam Annotations

Number of structural domains4
Mean domain length (aa)136 ± 16 aa
Standard deviation of domain lengths15.55
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score72.85
Mean fraction of residues predicted as intrinsically disordered0.95
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)62.59
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067N9B2 1-110 MSELIRRVNSMPGSPFATSPAARTGSAYSPYLKTSKSTLSRIAPLHPNRRAPPPPPPPPPPKKKTKKEIEREEKWEEELIESLGGLD…
A8NTR0 738-874 MSAPVAKPFHRRPSIAPRKSTPMTELIKRVNSLPNSPFPVASSARVPGISRATAYSPYLKSSRTALSKIAPLHPNRRTPPPPPPPPP…
A0A067TFY1 790-936 None
A0A5C3LJB6 781-929 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.