DPCstruct | MC42109

Metacluster Properties and Pfam Annotations

Number of structural domains287
Mean domain length (aa)275 ± 49 aa
Standard deviation of domain lengths48.96
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.40
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)14.85
Pfam Score94.60
Assigned Pfam label(s) CL0059- PF00557- CL0613- PF00067- CL0429

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L9ZKF2 160-450 CPFSDEINPHAEEVRAQSQEWAQELGMIDEPSQRIDTVSRLGCQLHPQASLESMQLCSDWYSWVFAHDDDLDPTELGTNPEAVESFH…
A0A386KZ50 102-449 FYCPFEPSLSPHYLELYGSRDERASIYETTMKKYNRINSEKTSAICTPYSSYGDTQIVAYFYSMMYYINDQTAHLKLPESEIESELI…
A0A4Y9TEF1 5-247 None
A0A0F7TXH9 1-210 None
A0A199VT57 692-988 None
A0A1V6PI15 2-306 None
A0A117NL83 13-258 None
S7PZ44 12-252 None
Q5AY20 2-349 None
A0A6A6ACK3 13-315 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.