DPCstruct | MC421

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)97 ± 16 aa
Standard deviation of domain lengths15.57
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score90.79
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)34.17
Pfam Score100.00
Assigned Pfam label(s) CL0479

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9K2N4 1-76 MTRNLDHRVEAAVKIHSKKLKHELLEMLEIQLRDNVKARYLNNKQTNEYVHNDEPICRSQIVIHNYLKSKAEEQEI
A0A2G9XNP0 2-100 YYFHNGGDPEIYSGSADWMPRNFKKRAEILYPIKNTALKSRIMDEILMTYLKDNVKARLMQPDGSYVRIKPKSGEKLVRSQNELIAI…
A0A7Y2NVT5 1-89 None
H1LIV9 1-79 None
A0A162FX58 1-82 None
A0A380ZUS0 1-78 None
A0A644Y4R0 540-637 None
A0A316P363 641-771 None
D4IVH2 1-71 None
A0A7V5C8E9 103-215 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.